Chemistry

Specializations

1. Theoretical and Computational Chemistry

The research includes the theoretical study of folding mechanisms and disulfide bond making/breaking mechanisms as those in specific proteins, Calculating and simulating the mechanochemical reactions, theoretical study of various stochastic processes in biology, proposing theoretical models for dynamics and reactivity of macromolecules present in a cell at the molecular level, using the simple tools of equilibrium and non-equilibrium statistical mechanics to name a few. Also of interest are, unusual types of diffusions, and diffusions driven by active noise.

Faculty Members

  • Prof. K. L. Sebastian
  • Dr. Debarati Chatterjee
  • Dr. Padmesh A.

2. Supramolecular Material Chemistry and Inorganic Chemistry

We are interested in developing next-generation supramolecular materials with the multifunctional capability and customize their functional properties for versatile applications in biomedicine to environmental remediation. This can be achieved by employing the concept of “molecular self-assembly” which underlies the formation of several complex biological structures. An overall grand challenge is to exploit the new insights obtained from this research programme to answer “as-yet-unsolved research questions” and to probe some fundamental research questions in supramolecular chemistry. We foresee that the outcome of our research interest would lead to the development of novel materials and devices to support both the existing and emerging technologies, aimed to give a positive impact on the environment and quality of life.

Faculty Members

  • Prof. K. V. Govindan Kutty
  • Dr. Shanmugaraju S.

3. Design, Synthesis and Applications of organic materials

We are focused on the design, synthesis, and applications of novel classes of organic macromolecules. In contrast to the small molecules, macromolecules have some unique properties that make them perfect fit for various applications which are otherwise challenging to meet. Synthesis of macromolecules in its absolutely pure form is still difficult to achieve. While the current trend in this field is focused on solving this issue, immediate next goal is how to get a hand on controlling the properties of the macromolecules which is crucial for making them an efficient candidate for a given application. The fact that properties of a macromolecule are not predictable from the properties of the building blocks adds up another dimension to the complexity of this field. We aim to work on developing novel strategy to synthesize a new class of organic macromolecules and most importantly modulate their properties by the custom synthesis of building blocks and tuning organic reactions. The novelty of our system is that we can precisely control the arrangement of multiple functional groups that leads to its structure, properties, and function. Taking together Porel group is ambitious to develop a platform for the rapid and economic production of manmade materials with tunable properties for enormous applications from material to biomedical science. Currently we are focused on developing chemo-sensor for toxic analytes and antibacterial and anticancer drugs based on the newly developed organic materials.

Faculty Members

  • Dr. Mintu Porel

4. Materials for Environmental Sustainability

We develop new solid materials that can accelerate the rates of chemical reactions that have high relevance to clean environment. Applications can range from finding a suitable green industrial process or a new catalyst for vehicles, to affordable food packages, air and purifiers. The bottlenecks associated with materials are our research interests. For example, minimizing the heterogeneity in sites and developing catalysts with earth abundant elements are two important material-related goals that we work on. Our approach is to understand the role of chemical synthesis in tuning the surface chemistry and its consequent effects on catalysis.

Faculty Members

  • Dr. Dinesh Jagadeesan

5. Chemical Biology

Faculty Members

  • Dr. Sushabhan Sadhukhan

6. Biophysical Chemistry

Faculty Members

  • Dr. Supratik Sen Mojumdar
     

Research Facilities

Laboratories / Research Centres

  • Chemistry Research Lab (Ahalia Campus)
  • Lab 1 (Sharing with other faculty members)
  • Central Instrumentation Facility
  • High Performance Computing Center (HPC)
  • Wet lab fully equipped for Inorganic Materials Synthesis

Research Equipments

Projects

No. Project Name Amount (in INR) Duration Funding Agency
1 Theoretical Modelling Of High Pressure Chemistry & Study of Unusual Molecular Systems Rs.3500000 2019 - 2024 DST INSPIRE
2 Mapping the folding/misfolding mechanism of SOD1 using single molecule fluorescence spectroscopy Rs.2870000 2020 - 2022 SERB - Start-up Research Grant (SRG)
3 Design and Synthesis of a Novel Class of Sequence-defined Macrocycles with Modular Post-synthetic Modification for Material and Biomedical Applications Rs.5364832 2020 - 2023 SERB - Core Research Grant (CRG)
4 Study of the interaction between synthetic sequence-defined macromolecules and lipid-membrane towards developing antibacterial and anticancer drug Rs.9968000 2020 - 2023 Ministry of Human Resource Development - STARS
5 Low-cost Test Kit for Fast Screening of Covid-19 Patients Rs.500000 4 months (April 2020 - August 2020) Federal Bank
6 Isolated Transition Metal Atoms on Defect- Engineered Graphene: Synthesis and Catalytic Oxidation of Indoor Volatile Organic Compounds Rs.3767070 2020 - 2023 SERB - Core Research Grant (CRG)
7 Synthesis, characterization and evaluation of TiO2 - polymer nanocomposite for photocatalytic oxidation of ethylene Rs.945000 2019 - 2021 Defence Food Research Laboratory
8 Identification of the Substrates of DHHC Palmitoyl Acyltransferases by Rational Design of Trifunctional Probe and Exploration of Protein S- Palmitoylation Rs.3674850 2019 - 2022 SERB Early Career Research Award (ECRA)
9 Reversible Diradical Mediated Self-Assembly Formation of Discrete Organic Cages for the Construction of Stimuli-Responsive Supramolecular Functional Materials Rs.3763000 2019 - 2022 SERB Empowerment and Equity Opportunities for Excellence in Science (EMEQ)
10 A novel class of functionally controlled macromolecules with tunable properties for material and biomedical applications Rs.3800000 2018 - 2023 SERB Ramanujan Fellowship
11 On the Role of Proton Transfer in Triggering Disulfide Bond Reductions in Biological Systems- A Computational Approach Rs.1020000 2016 - 2019 SERB Start - Up Research Grant
12 Design of heterogeneous catalysts to improve the selectivity of high-temperature, gas - phase reactions Rs.1365654 2013 - 2019 SERB Ramanujan Fellowship

Faculty

Dr. Debarati Chatterjee

Assistant Professor
Email ID: debarati@iitpkd.ac.in
Contact Number: 04923 226 344
https://iitpkd.ac.in/people/debarati

Research Interests

  • Soft Condensed Matter System

  • Theoretical Biophysics

  • Equilibrium and Nonequilibrium Statistical Mechanics

  • Structure and dynamics of Macromolecules

Dr. Dinesh Jagadeesan

Assistant Professor
Email ID: d.jagadeesan@iitpkd.ac.in
Contact Number: 04923 226 345
https://iitpkd.ac.in/people/djagadeesan

Research Interests

  • Heterogeneous Catalysis

  • Environmental Chemistry

  • Materials Chemistry

Dr. Mintu Porel

Assistant Professor
Email ID: mintu@iitpkd.ac.in
Contact Number: 04923 226 346
https://iitpkd.ac.in/people/mintu

Research Interests

  • Design and Synthesis of Organic Materials
  • Chemosensor for Toxic Analytes
  • Antibacterial and Anticancer Drug Development

 

Dr. Padmesh A.

Assistant Professor
Email ID: padmesh@iitpkd.ac.in
Contact Number: 04923 226 342
https://iitpkd.ac.in/people/padmesh

Research Interests

  • Mechanochemistry of ring opening reactions.
  • Bond breaking mechanisms of protein disulfides.
  • Folding mechanisms in proteins.
  • Organic electronic materials.

Dr. Shanmugaraju Sankarasekaran

Assistant Professor
Email ID: shanmugam@iitpkd.ac.in
Contact Number: 04923 226 347
https://iitpkd.ac.in/people/shanmugam

Research Interests

  • Supramolecular Self-assembly Formation of Discrete Molecular Architectures
  • Engineering Mesoporous Polymers for Environmental Remediation Applications
  • Fabrications of Functional Bio-Nanostructures for Biomedical Applications
  • Synthesis of Chemosensors for Biologically Related Analytes
  • Development of Novel Theragnostic Agents for Cancer Therapy

Dr. Supratik Sen Mojumdar

Assistant Professor
Email ID: supratik@iitpkd.ac.in
Contact Number: 04923 226 348
https://iitpkd.ac.in/people/supratik

Research Interests

  • Protein folding/misfolding and aggregation mechanism
  • Protein chaperone/small molecule interaction
  • Protein conformational dynamics
  • Role of post translational modification on protein folding

Dr. Sushabhan Sadhukhan

Assistant Professor
Email ID: sushabhan@iitpkd.ac.in
Contact Number: 04923 226 349
https://iitpkd.ac.in/people/sushabhan

Research Interests

  • Chemical Biology
  • Bio-organic Chemistry
  • Drug Discovery & Delivery
  • Cancer Cell Metabolism
  • Metabolomics & Proteomics

Prof. K. L. Sebastian

Professor
Email ID: sebastian@iitpkd.ac.in
Contact Number: 04923 226 511
https://iitpkd.ac.in/people/sebastian

Research Interests

  • Quantum Chemistry
  • Statistical Mechanics

Prof. K. V. Govindan Kutty

Professor
Email ID: kvg@iitpkd.ac.in
Contact Number: 04923 226 341
https://iitpkd.ac.in/people/kvg

Research Interests

  • Materials Chemistry