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IIT Palakkad has signed a Memorandum of Understanding with Centre for Management Development, Thiruvananthapuram on 13 June 2023. The MoU was formalized officially by Prof. A Seshadri Sekhar (Director, Indian Institute of Technology Palakkad) and CA. Dr. Binoy J. Kattadiyil (Director & Member Secretary, CMD Trivandrum). The MoU is expected to leverage complementary expertise in joint organization of seminars, conferences, workshops and short-term courses, research, faculty exchange programs etc.

IIT Palakkad has signed an agreement with the Indian Institute of Technology Indore on 28 February 2023. With this agreement, the parties agree to conduct a collaborative research project titled "Development of an affordable wearable IoT-GPS enabled intelligent vital signs monitor for smart health monitoring services" for addressing the major design, development and deployment issues by considering the improvement of diagnostic accuracy and reliability, false alarm reduction, affordability, and battery lifetime. The project is being funded by the Indian Council of Medical Research (ICMR) and is being executed by Prof. Ram Bilas Pachori, Professor, Department of Electrical Engineering, IIT Indore and Dr. M. Sabarimalai Manikandan, Associate Professor, Department of Electrical Engineering, IIT Palakkad.

IIT Palakkad signed an MoU with the NSS College of Engineering Palakkad on 22 February 2023. The MOU covers bilateral collaboration of academics and research between the two institutions such as Conducting programmes to achieve desirable objectives in connection with capacity building, Exchange of information on research and educational programmes, Joint organization of seminars, conferences, workshops, and short- term courses, Joint supervision of MTech projects by faculty members from both the institutes, joint project proposals, visiting fellow program, and Student internships between both the institutes. The MOU was signed by Dr. Santhakumar Mohan, Dean- ICSR, IIT Palakkad and Dr. Anand T.N.C., Dean- Academics, IIT Palakkad with Dr. Suresh P.R., Principal, NSS College of Engineering.

IIT Palakkad signed an MoU with College of Engineering Trivandrum on 14 February 2023. This MoU will facilitate cooperation and promotion of Academic and Research & Development projects in Science, Technology, and Engineering, joint organisation of conferences, workshops and seminars, student internships across both institutions, and joint supervision of projects. The MoU was signed by Dr. Santhakumar Mohan, Dean - Industry Collaboration and Sponsored Research and Dr. Suresh Babu V., Principal of  College of Engineering, Trivandrum in the presence of Prof. Seshadri Sekhar, Director IIT Palakkad and Dr. Suneesh S. S., Professor & Head of Mechanical Engineering, College of Engineering Trivandrum. Dr. Jobin Francis, Assistant Professor, Electrical & Electronics Engineering, IIT Palakkad is the faculty in-charge for this MoU.

IIT Palakkad signed an MoU with Rajiv Gandhi Institute of Technology (Government College of Engineering), Kottayam on 01 December 2022.  This MoU will facilitate cooperation and promotion of Academic and Research & Development projects in Science, Technology, and Engineering, joint organisation of conferences, workshops and seminars, student internships across both institutions, and joint supervision of projects. The MoU was signed by Dr. Santhakumar Mohan, Dean - Industry Collaboration and Sponsored Research, and Dr. Sathish, Principal of RIT Kottayam, in the presence of Dr. Sovan Lal Das, Dean - Academics, and Dr. Selvapandian, Industry Liaison Officer. D.r Santhakumar Mohan, Associate Professor, Mechanical Engineering is the faculty in-charge for this MoU between IIT Palakkad and RIT Kottayam.

A Memorandum of Understanding between Government Engineering College (GEC), Wayanad and IIT Palakkad was signed on January 17, 2023 at Nila Campus. It was formalised to facilitate and promote academic collaboration, research and development projects in Science, Technology and Engineering, joint organisation of conferences, workshops and seminars, and student internships between both the Institutions. The MoU was signed by Dr Santhakumar Mohan, Dean, Industry Collaboration and Sponsored Research, IIT-PKD and Dr Anitha VS, Principal, GEC Wayanad, in the presence of Dr Sovan Lal Das, Dean, Academics. Dr Vijay Muralidharan is the faculty-in-charge for this MoU between IIT Palakkad and GEC, Wayanad.

IIT Palakkad has signed a MoU with the Centre for Adivasi Research and Development (CARD), Odisha on 31 October 2022. This MoU will facilitate cooperation and promotion of research and development in the sectors of fundamental training on Science, Technology, and Engineering for women of the marginalized community, Research and development projects for the benefit of underprivileged communities, Adhivasi, SCC/ST, and other tribal population, Research and development projects to address the issues of environment, sanitation, water resources, and natural habitat. Besides research in areas of mutual interest, the MoU will assist the integral efforts of CARD for specific studies in the areas of Adhivasi research, under privileged community projects and in connection to other critical projects of significance.The MoU was signed by the Director Centre for Adhivasi Research & Development (CARD), Dr Bikram Keshori Jena, and Dean Industry Collaboration and Sponsored Research, Dr Santhakumar Mohan.  Dr Deepak Jaiswal, from Environmental Sciences and Sustainable Engineering Centre (ESSENCE) is the faculty in - charge for MOU between IIT Palakkad and Centre for Adhivasi Research and Development (CARD) Odisha.

IIT Palakkad has signed an MoU with the Kerala Forest Research Institute (KFRI) operating under the aegis of the Kerala State Council for Science, Technology and Environment (KSCSTE) on 18 October 2022. The MoU will facilitate collaborative research, practice and engagement between the two Institutes in areas of mutual interest like Developing the Green Campus at IIT Palakkad's upcoming permanent site, Addressing human-animal conflict, Addressing and modeling the carbon sequestration potential of different bamboos species, Sea-shore restoration, Landslide prediction and hydrological modeling, Large-scale application of bamboo and rattan in the construction sector, Molecular modeling, Developing instruments for sustainable harvest of Non-timber Forest Produce (NTFPs), Climate change prediction and modeling using plant functional traits, Identifying and quantifying invasive species of plants through image processing, Understand the behaviour pattern of invasive tortoises which are caged on the KFRI campus by recording and mapping the movement of each individual, Machine learning Algorithms for gene sequencing, Identifying suitable varieties of bamboo to develop a support frame for floating solar panels, Student, faculty, scientist, and staff exchange programmes and cooperation between them in appropriate academic and scientific programmes, Exchange of scientific and technical materials & Joint conferences and workshop.